Normal Is Not Optimal

At Optimize U we empower you to feel your best. We specialize in helping individuals break free from the confines of ‘normal’ and discover their path to optimal well-being.

Do You Struggle With

We’re here for you

Our Services

Optimize U can help you feel better Mentally… Physically… and Sexually!

Cryotherapy

  • Makes you feel better
  • Improves angle of motion
  • Quickens athletic recovery
  • Increases vitality
  • Improves anti-aging
  • Triggers weight loss
  • Boost Performance
  • Enables muscle relaxation
  • Reduces inflammations

IR Saunas

  • Better sleep
  • Burn calories
  • Improve circulation
  • Clearer tighter skin
  • Ease chronic fatigue

Compression

  • Better sleep
  • Decrease inflammation
  • Reduce swelling
  • Recovery more quickly and get back to doing what you love.

Peptides

  • Sleep Quality
  • Muscle Mass
  • Tissue Healing
  • Digestive funtion

M.I.C.

  • Better sleep
  • Burn calories
  • Improve circulation
  • Clearer tighter skin
  • Ease chronic fatigue

G.A.C.

  • Better sleep
  • Decrease inflammation
  • Reduce swelling
  • Recovery more quickly and get back to doing what you love.

Mission and Values

At Optimize U, our mission is to make a meaningful difference in the lives of individuals seeking better health and wellness. We are guided by a set of core values that reflect our unwavering commitment to you. Our dedication to these principles ensures that you receive the care and support you deserve on your journey to optimal health.

Accessible

We ensure healthcare services are accessible to everyone.

Affordable

We work tirelessly to provide cost-effective solutions.

Excellence

We continuously strive for clinical and service excellence.

Empowerment

We empower individuals to take control of their health.
5 Star Reviews
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Years Medical Experience
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Expert Clinicians, Patient-First Care

At Optimize U, you’ll receive tailored healthcare from professionals who make your well-being their top concern.

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Clinician Run

Our clinics are all run by licensed and trained healthcare professionals whose passion is making a difference in your life.

Clinician Led

By focusing on professionalism and friendliness, we empower our clinics to provide you the best care you’ll find anywhere.

Patient-Focused

We’re more than a clinic. We know our patients. We learn your unique needs. And we provide the care you need to live your healthiest life.

Revitalize Your Life

Explore our extensive array of services designed to align with your unique goals and aspirations.

Optimize Your Health
In 4 Easy Steps

Discover Your Personalized Roadmap to Wellness and Unleash Your Full Potential

Contact Us To Start​

Contact our office via phone or our web contact form. This will give us the information we need to get started.​

Get Your Labs​

To begin the process we draw blood to find out where you are. You can have this done at our location or any LabCorp.

Make an Appointment

We will set an appointment for you to meet with one of our providers to review your labs and determine the next steps.

Contact Us To Start

We will discuss the various treatment options and choose the one that best suits your goals.

1

Contact Us To Start

Contact our office via phone or our web contact form. This will give us the information we need to get started.

2

Get Your Labs

To begin the process we draw blood to find out where you are. You can have this done at our location or any LabCorp.

3

Make an Appointment

We will set an appointment for you to meet with one of our providers to review your labs and determine the next steps.

4

Contact Us To Start

We will discuss the various treatment options and choose the one that best suits your goals.

1

Contact Us To Start

Contact our office via phone or our web contact form. This will give us the information we need to get started.

2

Get Your Labs

To begin the process we draw blood to find out where you are. You can have this done at our location or any LabCorp.

3

Make an Appointment

We will set an appointment for you to meet with one of our providers to review your labs and determine the next steps.

4

Contact Us To Start

We will discuss the various treatment options and choose the one that best suits your goals.

Read Our Reviews​

5.0
Based on 167 reviews
powered by Google
David
18:07 11 Dec 25
Great experience, happy with all treatment and follow ups. 10/10 would recommend.
David
18:07 11 Dec 25
Great experience, happy with all treatment and follow ups. 10/10 would recommend.
idURKk
21:26 10 Dec 25
I’m a very anxious person when going into a doctors office, I felt very comfortable from the get go, & everyone was super nice, & very knowledgeable about any questions I had. Will definitely recommend to anyone!
idURKk
21:26 10 Dec 25
I’m a very anxious person when going into a doctors office, I felt very comfortable from the get go, & everyone was super nice, & very knowledgeable about any questions I had. Will definitely recommend to anyone!
James Phillips
00:20 07 Dec 25
I've been using Optimize U for 4 year's for TRT and Tyroid treatment. For 2 of those year's I was still competing in Bodybuilding at 49 year's old. Now I'm just living a healthy lifestyle. I dropped the thyroid therapy cause I no longer needed due to having a healthy thyroid. Getting blood work done every 3 months is important to me to keep an eye what my healthy is doing. Dylan always calls we have a nice chat. He goes over everything and if he sees something that needs attention we address it. Everything is always minor with me. We add a few vitamins, he recommends trusted products that they don't sell. If you are on the fence I highly recommend these guys they are terrific!!!!
James Phillips
00:20 07 Dec 25
I've been using Optimize U for 4 year's for TRT and Tyroid treatment. For 2 of those year's I was still competing in Bodybuilding at 49 year's old. Now I'm just living a healthy lifestyle. I dropped the thyroid therapy cause I no longer needed due to having a healthy thyroid. Getting blood work done every 3 months is important to me to keep an eye what my healthy is doing. Dylan always calls we have a nice chat. He goes over everything and if he sees something that needs attention we address it. Everything is always minor with me. We add a few vitamins, he recommends trusted products that they don't sell. If you are on the fence I highly recommend these guys they are terrific!!!!
Kyle Hawley
22:08 04 Dec 25
Kyle Hawley
22:08 04 Dec 25
Andrew Dillon
16:31 03 Dec 25
I have been a client of Optimize-U of Louisville for over a year, and the experience has been exceptional. Their comprehensive approach—including CBC panel monitoring, supplement guidance, and personalized diet recommendations—has consistently supported my health and fitness goals.I primarily work with Dylan Martin, RN, whose dedication and investment in my well-being have been outstanding. His expertise and genuine concern make the process both effective and enjoyable.If you are committed to improving your health and prefer a proactive approach over spending time in a doctor’s office addressing preventable issues, I highly recommend Optimize-U of Louisville. Their team will help you achieve—and potentially exceed—your wellness goals.
Andrew Dillon
16:31 03 Dec 25
I have been a client of Optimize-U of Louisville for over a year, and the experience has been exceptional. Their comprehensive approach—including CBC panel monitoring, supplement guidance, and personalized diet recommendations—has consistently supported my health and fitness goals.I primarily work with Dylan Martin, RN, whose dedication and investment in my well-being have been outstanding. His expertise and genuine concern make the process both effective and enjoyable.If you are committed to improving your health and prefer a proactive approach over spending time in a doctor’s office addressing preventable issues, I highly recommend Optimize-U of Louisville. Their team will help you achieve—and potentially exceed—your wellness goals.
Kristen Estes
21:20 07 Nov 25
All of the staff and doctors are so friendly and helpful. They go out out of their way to make you feel truly cared for and heard. I can’t recommend it enough. It’s been completely life-changing!
Almira Quan
15:38 06 Nov 25
Jessica is amazingBeautiful friendly and very knowledgeableGreat experience
Nancy Martis
07:37 16 Oct 25
Very knowledgeable and caring. I'm so excited to get my life and health back. It's never to late to start.
Kevin Willis
17:10 29 Sep 25
Staff was great.Easy experience.Doctor was amazing
Christy Hall
20:06 24 Sep 25
I had my first appointment with Rachel today. She was so understanding & knowledgeable, im excited to work with her and Oprimize U to get my health back on track! The ladies at the front are super sweet & helpful too. Overall great experience and I highly recommend reaching out to see what they have to offer!
Jeremy Maudlin
18:45 30 Jul 25
Pleasant friendly and informative
Justin
19:22 25 Jul 25
Andy Conrado
22:33 17 Jun 25
♥️💪🔥🙏
Samantha Hufford
18:29 11 Jun 25
I had a great consultation with Jessica! Super knowledgeable and informative. I am super hopeful that our treatment plan will get me to feeling great again!
Will Jackson
17:05 29 May 25
Jeremy McManaway
12:17 21 May 25
Michael Shaheen
13:52 16 May 25
David Bufford
23:25 14 May 25
Heiko Myers
20:48 14 May 25
2 years and I haven't felt this good 25 years. Polite professional friendly helpful and knowledgeable. I could barely get out of bed in the morning and my son dragged me here and changed my life. Seriously I never knew a place like this existed and I am eternally grateful. God bless you all. I can never thank you enough.
Jen Mills
18:56 02 Apr 25
Santi Ramirez
18:14 28 Mar 25
Great customer care. Knowledgeable and professional staff.
Xavier Hunter
13:38 15 Mar 25
Really great folks in this establishment. Professional and knowledgeable always thankful for their readiness and accessibility. Keeping Kentucky healthy!
Clay Caple
13:26 15 Mar 25
Very quick and easy.Also very informative
Joe Scott
13:24 15 Mar 25
JEWELL and DYLAN will take care of you!!! Optimize you is the only place to go!!!
Holly Thrasher
14:49 24 Jan 25
Great place. Excellent customer service. Caring and compassionate!
Terra Renae
15:09 22 Jan 25
I couldn’t speak higher of OptimizeU! Everyone is so kind, professional and unbelievably knowledgeable! I appreciate that they truly take the time to listen to my concerns and create a completely customized treatment plan for me! I’m loving the results!!!
Brad Christiana
15:40 15 Jan 25
Jessica Matise and her staff provided excellent care. She was always available to answer my questions, my health and wellbeing was her primary concern.
Bryan Fiscus
18:04 14 Jan 25
lisa Nalley
17:10 02 Jan 25
I absolutely love OptimizeU Louisville. They have helped me turn my health around and I feel so much better. It’s only been a year now and I wish I had started this journey earlier. Thank you Rachel and Dylan and all the other amazing staff! Keep up the great work! Love you all! ❤️
William Johnston
17:34 16 Dec 24
I love their sauna and cold plunge. It's definitely an extremely intense process, but it helps tremendously with pain relief.
Rhonda Abbott
20:47 10 Dec 24
Extremely kind & helpful staff. Very pleasant experience, I won't be going anywhere else!
Valerie Arnold
16:29 09 Dec 24
Such a great experience! Dr. Jessica Matts has helped me understand and educate me about my POCS. When I first went to Optimize U it was just to check my horomones for body building purposes but I got so much more.For 4 years I thought something was seriously wrong with my menstrual cycle between the extremely short and heavy periods to mood swings so bad I thought I was possessed!! I seen several doctors who told me everything was fine.. it’s just my horomones.. “I was a lucky one to only have a 2 day period”..Fast forward to 4 YEARS LATER.. the wonderful Dr. Matt’s gave me so much insight and help me understand I have POCS! This has been life changing for me!
Steven Best
19:32 03 Dec 24
Great friendly service representatives and fantastic customer care.
kristan harmon
17:37 21 Nov 24
My husband and I both started here for various different services and love it. The facility and staff are all top notch!
Lisa Livers
20:51 14 Nov 24
I have been going to Optimize U for over a year now. I can't say enough great things about them. Rachel is who I deal with the most and she is absolutely the best. She always answers all my questions and always has my best interest in mind. I feel so lucky to have found Optimize U. I have lost about 25-30 pounds, and they have put me on hormone therapy which has made all the difference. If you are having any issues I highly recommend. From weight loss to hormones, I am so thankful. I can't imagine going anywhere else. They are all so friendly and so helpful. Call today you will not be sorry!!
KERI LOCK
11:29 14 Nov 24
I have had a very positive experience with Optimize U. Rachel and Dylan have helped me navigate my struggles through perimenopause. Rachel is always responsive and thorough with her feedback. I have already referred 2 of my friends who were not having a good experience with their providers. I highly recommend Optimize U. So glad I found them!
James Lock
11:24 14 Nov 24
Amazing staff and service! Rachel and Dylan are incredibly professional, knowledgeable, and responsive. Whenever I have a question, I can get an immediate response. The hormone therapy has been a game changer for me. I HIGHLY recommend Optimize U!
thomas sauer
04:24 11 Nov 24
Best place to go to hands down. No sales gimmick, they give you the best advice for you and not just what is good for business. I have had questions outside of my office visits and they are quick to respond. I don’t know why you would go anywhere else.
Michael Johnson
18:29 31 Oct 24
Absolutely amazing facility, can’t recommend enough.
Billy Wilson
06:00 18 Oct 24
G M
21:08 14 Oct 24
Tara Myers
21:50 02 Oct 24
Going to Optimize U has helped my mind and body be the best it can be. They will help you to feel your true you than anywhere else. Call them, you wont regret it
Chelsie Brown
19:12 09 Sep 24
Shelby Nichols
19:11 09 Sep 24
You guys are the best!
Tyler Woods
17:14 01 Aug 24
I was taken care of and given an extensive conversation and wealth of knowledge given my hormonal/weight loss needs. Haven't recieved medicine yet, but the practitioner and her nurses are wonderful to speak with. Say hi to Biggie if ya stop by!
Christopher Beverley
20:33 31 Jul 24
Yuri
13:03 22 Jul 24
Tyler
22:17 12 Jul 24
Great experience! 10/5 😜 Seriously, great experience though! Everyone was super nice, clean, wait time was not long at all. Dr. Jessica explained everything very well while going over results and straight to the point. Looking forward to treatment. Oh…parking was a breeze also. In and out in 25-30 minutes.
Christine Lund
16:24 02 Jul 24
Highly recommend this place to get your hormones checked. I worked with Rachel and she made me feel so good telling me hormonal numbers.
Thor’s Groot
15:33 25 Jun 24
Optimize U has been nothing but amazing. The results from the treatments have truly met all of my desired wish and wants. The staff from the front end receptionist to the medical staff have been TOP NOTCH! Every time I've called for any question big or small i am immediately greeted with a friendly voice that takes time to listen to my question. All medical appointments have been on point and very helpful. The medical staff take the time to listen while speaking with them without any distractions. If i could recommend this place i would 1,000 times again.
countryboy1291
15:28 18 Jun 24
I am in the beginning stages of my TRT treatment. Optimize U has been extremely friendly throughout the process. They answered all my questions and explained all the information in a very understanding way. I would highly recommend anyone who wants to know if TRT is right for them, go to Optimize U
John Miller
03:12 04 Jun 24
Great service and feeling great after a year!
Cortney Etherton
20:55 09 May 24
Dylan, Rachel and the staff are amazing. Very friendly, knowledgeable and keep up on the most recent technology and treatments. Highly recommend!
Meghan Mcpeek
15:18 03 May 24
Friendly professional atmosphere. I’m looking forward to using Optimize for my health needs!
Savannah Evans
19:43 24 Apr 24
Carmen Jamison
18:47 08 Apr 24
Jessica is amazing and easy to talk to. She helped me decide best treatment for me and answered all my questions. Her staff is also amazing. I would highly recommend them.
Danielle McHatton
19:11 05 Apr 24
Austin B
18:01 05 Apr 24
mitch fuzy
18:29 04 Apr 24
Fantastic staff, excellent facilities, and awesome results.
Haley Jackson
17:34 04 Apr 24
Best pricing for blood work. The staff is very friendly and extremely knowledgeable especially for all my pre and post prep needs! Highly recommend.
Yvonne Gemmer
14:53 01 Apr 24
Amy Davis
17:33 05 Mar 24
I have always had a great experience when I visit Optimize U. The staff is top notch! If you’re thinking about going - go! I have never felt better.
Megan ward
13:53 05 Mar 24
Great staff all the way around. Coming to a clinic with all sorts of emotions and leaving feeling more confident and hopeful is more than I could ever have hoped for. Thankful for this clinic!
Randall007 S
17:25 01 Mar 24
Dylan Martin
20:39 27 Feb 24
I’m a returning customer very happy to work with this team. Dr. Jessica is knowledgeable and made me feel like she would take the time to really listen to me. Very different than most of my Dr office visits over experienced over the years.
Lane Whelan
17:02 27 Feb 24
Brad Blankenship
17:55 09 Feb 24
Great products and service
Daniel Goldberg
22:04 08 Feb 24
I've been with Optimize U for two and a half years. I have nothing but good things to say about my treatment and results!
Angela Z
23:38 06 Feb 24
Aree T
18:28 06 Feb 24
Today, I went into Optimize U for skin concerns. Rachel and I talked about my concerns and what I wanted to achieve. Going over some options and what she suggested we came to an agreement what the game plans is. I can’t wait to get started! Thanks Rachel and staff at Optimize U for your professionalism and listening to my concerns. Love you all, & Biggie!
Julian Johns
17:59 06 Feb 24
They took my blood and I was in/out in about 10 minutes. I got my labs back in a convenient amount of time and my consultation was one day after that which was awesome! Everyone was great and easy to work with from top to bottom.
Terra Schrembs
20:38 22 Jan 24
I LOVE this place!!! Everyone is so friendly and passionate about what they do. I really appreciate that the providers take the time to genuinely listen to my concerns, and I never feel rushed. They offer a fine array of services and customized treatment options! So happy to have found OptimizeU!
outdoors & more
20:47 19 Jan 24
Rachel was very professional and polite. She answered all my questions and was very knowledgeable.
Tanya S
23:25 09 Jan 24
The office staff is friendly and I just really like Jessica. She has really helped me with my hot flashes and night sweats. She makes sure that the medication is working and that it’s the correct dose. Everyone should go see her and find out for yourself
Adam Clark
20:28 05 Jan 24
Ryan Hawkins
20:30 21 Dec 23
Autumn Cleveland
22:04 19 Dec 23
I have been coming here for my own health for years, and I have loved they handle each treatment and protocol…so much that I recommend all of myClients and friends to them, because I trust them. They explain everything throughly, are not pressuring, and they are genuine and caring people.
David Lara
13:15 11 Dec 23
Very good and professional team.
Kathy Wesley
16:40 06 Dec 23
I always love my trips to OptimizeU. The ENTIRE staff is so friendly and knowledgeable. I always feel so good about myself when I leave there. I could sit and chat with them all day.
Yilian Velazquez
17:51 05 Dec 23
Jessie Conlin
19:47 15 Nov 23
I'm super happy with my experience at Optimize U. Everyone there is friendly, attentive, and knowledgeable. Rachel explained everything clearly and answered all my questions. She also provided me with a customized plan that suited my needs and goals. I'm so excited to see the progress I'll be making. Highly recommend!!!
Tara Myers
19:55 13 Nov 23
You won’t go wrong coming here!! They’re better at helping you become your best self than anywhere I’ve ever dealt with. The staff is top notch!
Meg Palmer
19:13 13 Nov 23
Aimee McCaa
00:29 07 Nov 23
Jessica Matis APRN is just wonderful. She listens, reviews labs in details and ask appropriate questions regarding my on going health. I am glad my hormonal care is in her hands. 🙌🏻
Andrew Bowen
20:01 06 Nov 23
So freaking awesome. Wonderful experience and care. They really know what they’re talking about there when it comes to hormones.
lisa byerly
19:49 20 Oct 23
Chadd T
21:15 16 Oct 23
Brian Sparling
22:24 14 Oct 23
Very professional wonderful informed staff… very pleased
Daniel Dunn
18:15 10 Oct 23
Very knowledgeable and straight forward with any and all aspects of TRT and its benefits!!!
shelby eisenback
15:30 02 Oct 23
My experience with Optimize U has been nothing short of amazing! The medical staff are extremely professional, and informative, and thoroughly explained everything I needed to know about semaglutide, and why it could assist me with reaching my weight loss goals. I have to give a special shoutout to Rachel, as she has been WONDERFUL to work with, and is extremely responsive to all of my questions I have had throughout this process. I also love that they offer the in-body scan to keep track of my weight loss progression, including fat loss and muscle gain. My husband heard me rave about my experience, and saw the success I am having with semaglutide, and decided to become a customer, too! I will continue to recommend Optimize U to all of my family and friends, and cannot wait to start to use their other amazing services.
Kim Joseph
17:09 28 Sep 23
Rachel is the best!!...They offer so many wonderful services. The staff is so welcoming as well.
Jackie Scotts
18:34 26 Sep 23
Ashley Branham
00:56 24 Sep 23
I have been so impressed with this clinic and their knowledge about how to optimize my weight loss journey. Rachel is awesome and so relatable! She’s a hype girl for sure ! They seem to a wonderful staff who really cares about the health of their patients!
Maja Guandique
19:39 14 Sep 23
Customer care is unmatched! Dylan is amazing at taking care of patients, is super knowledgeable, and always goes the extra mile!
Aaron Kaplan
18:08 09 Sep 23
Terra Renee Arla
19:52 16 Aug 23
I am so impressed with Rachel's knowledge and professionalism. She thoroughly discussed my treatment and ensured my comfort throughout the duration of my visit. I am about 1 month into my Sculpt series, and I am already seeing drastic results on my once stubborn abdominal area. I also want to mention that the entire staff is so friendly and always makes me feel right at home. OptimizeU is truly a one stop shop filled with knowledgable professionals eager to help you reach your goals!
Rachel Ray
16:49 20 Jul 23
Love this business and my experience with them! The staff is so helpful to direct you to all options to achieve your goals. Dr Jessica is very knowledgeable about hormones and can help you better understand your lab panel. I’m so thankful I found them!
Marshall Mummert
20:13 06 Jul 23
Great place, great service. Friendly knowledge staff.
John Miller
21:22 21 Jun 23
So thankful I found Optimize U! The service is far better than any place I have ever been and they are very well educated on any question you may have. Friendly staff and a great environment. Love the fact that I have stepped outside my comfort zone and given Cryotherapy a try. Totally worth it! It’s TWO THUMBS UP from me!
Ashley Yoerg
18:02 21 Jun 23
I can not say enough good things about Optimizeu. The facility is immaculate, but also inviting. The staff is friendly, skilled and professional. The services I have received were performed accurately and efficiently in regards to time. I would highly recommend Optimizeu to any friend or family member.
Derek Gronda
23:03 20 Jun 23
After searching several places I came across optimize and haven’t looked back. Friendly professional and very knowledgeable staff. At 42 I’m thriving and crushing at life again, in all aspects. I’ve recommended several people by word of mouth including those closest to me, now I’m recommending you. If you’re reading this, chances are you’re not feeling yourself these days, not the best you can/could be, do yourself a favor and invest in yourself, your mental and physical health. Be the best you can be, thank me later!
Mary Meyer
20:54 06 Jun 23
I’ve been to Rachel several times for microneedling and Botox. She takes great care of me. She guides me to pick the treatments that will best meet my skin care goals. She takes a lot of time to make me feel comfortable. She’s very diligent about properly numbing me before the treatments that require it. She also keeps an open line of communication after treatments and can easily be reached if I have any follow-up questions or concerns. I cannot recommend her services enough. The treatment rooms are very clean, and the design is awesome. I tell everyone that I know that they need to go see her for any of their hormone or skin concerns.
Chelsie Skillman
03:41 31 May 23
I really have to have a lot of trust in the people taking care of me, and I definitely found that in Rachel at optimize U. I would send any of my family to her and know that they would be in great hands. I went to optimize U to get labs and an IV.The IV menu is super fun and I love all the options but Rachel was great & helped me choose based off of my overall goal for therapy. While my IV was going I got to sit in the most comfortable massage chair and watch TV, while Rachel checked on me multiple times. It was the most relaxed I’ve been in a while. Everything is very clean and it has the cutest decorations! I’m looking forward to monthly treatments to boost my health and wellness! I even had follow up for a semaglutide consult.Just all around good vibes, you can’t go wrong with anything here.
Juliana V
20:30 30 May 23
Optimize U is this magical place where you become the best version of yourself! My entire life, I had always struggled to lose weight and get in shape - I tried just about every exercise/ dieting program and then reached a point where I just accepted that this is the way I would always look. Jessica and Rachel, along with the entire Optimize U team, were able to meet me where I was at and help me gain control of my life. The Semaglutide injections helped me with my weight loss journey and allowed me to finally feel confident in my own skin for the first time ever - And I’m very excited to try Mounjaro next!Since having found out about Optimize U, and all of the services they provide, I have also become a huge fan of micro-needling and Dysport! After having these treatments, my face and skin look healthier and more vibrant than ever. Especially going into the summer months, it makes such a difference not feeling like you need to wear makeup to cover up all of those imperfections and wrinkles.I also have struggled with hair thinning which, as a woman, has made me feel very self conscious. Rachel introduced me to Nutrafol and it has made SUCH a difference! I have been taking Nutrafol along with Reds & Greens since December and my hair dresser has been amazed by all my new hair growth.Finally, I can’t say enough about the staff at Optimize U. They always make me feel so comfortable and validated in my expectations of what I am looking to achieve for myself. Jessica and Rachel are extremely knowledgeable about all of their products and services and I am so grateful for them!
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Discover the Optimize U Difference

Proven Experience

Our clinic is run by licensed and trained healthcare professionals whose passion is making a difference in your life. We pride ourselves on being up to date on all of the latest information to ensure optimal care.

Affordable Care

With our all-in-one pricing, you receive Hormone Optimization, ongoing lab work, office visits, supplies, and Recovery at one low price. While other clinics often have to raise their pricing due to inflation, we work constantly with our partner pharmacies and lab companies to ensure pricing will always be affordable.

Longer Consultations

Ever wanted to spend an hour with your practitioner to make sure all of your questions have been answered? You got it, we will spend as much time as needed with you to ensure you are comfortable and knowledgeable about your journey to optimize your life.

Delivered to Your Door

Don’t worry about having to go to a pharmacy, we send your medications directly to your doorstep in a discrete box for your convenience. When you’re ready for a refill, just let the staff know and they will get your next order on its way to your door.

Meet Our Team

Meet the medical experts who are here to guide you on your path to optimal health.

Dylan Martin RN

Rachel Killen MSN, APRN

Practitioners

Jessica Matis DNP, APRN

Practitioners

Paul Weinberger MD

Register Us

Louisville, Kentucky

read Our Reviews

5.0
Based on 167 reviews
powered by Google
David
18:07 11 Dec 25
Great experience, happy with all treatment and follow ups. 10/10 would recommend.
David
18:07 11 Dec 25
Great experience, happy with all treatment and follow ups. 10/10 would recommend.
idURKk
21:26 10 Dec 25
I’m a very anxious person when going into a doctors office, I felt very comfortable from the get go, & everyone was super nice, & very knowledgeable about any questions I had. Will definitely recommend to anyone!
idURKk
21:26 10 Dec 25
I’m a very anxious person when going into a doctors office, I felt very comfortable from the get go, & everyone was super nice, & very knowledgeable about any questions I had. Will definitely recommend to anyone!
James Phillips
00:20 07 Dec 25
I've been using Optimize U for 4 year's for TRT and Tyroid treatment. For 2 of those year's I was still competing in Bodybuilding at 49 year's old. Now I'm just living a healthy lifestyle. I dropped the thyroid therapy cause I no longer needed due to having a healthy thyroid. Getting blood work done every 3 months is important to me to keep an eye what my healthy is doing. Dylan always calls we have a nice chat. He goes over everything and if he sees something that needs attention we address it. Everything is always minor with me. We add a few vitamins, he recommends trusted products that they don't sell. If you are on the fence I highly recommend these guys they are terrific!!!!
James Phillips
00:20 07 Dec 25
I've been using Optimize U for 4 year's for TRT and Tyroid treatment. For 2 of those year's I was still competing in Bodybuilding at 49 year's old. Now I'm just living a healthy lifestyle. I dropped the thyroid therapy cause I no longer needed due to having a healthy thyroid. Getting blood work done every 3 months is important to me to keep an eye what my healthy is doing. Dylan always calls we have a nice chat. He goes over everything and if he sees something that needs attention we address it. Everything is always minor with me. We add a few vitamins, he recommends trusted products that they don't sell. If you are on the fence I highly recommend these guys they are terrific!!!!
Kyle Hawley
22:08 04 Dec 25
Kyle Hawley
22:08 04 Dec 25
Andrew Dillon
16:31 03 Dec 25
I have been a client of Optimize-U of Louisville for over a year, and the experience has been exceptional. Their comprehensive approach—including CBC panel monitoring, supplement guidance, and personalized diet recommendations—has consistently supported my health and fitness goals.I primarily work with Dylan Martin, RN, whose dedication and investment in my well-being have been outstanding. His expertise and genuine concern make the process both effective and enjoyable.If you are committed to improving your health and prefer a proactive approach over spending time in a doctor’s office addressing preventable issues, I highly recommend Optimize-U of Louisville. Their team will help you achieve—and potentially exceed—your wellness goals.
Andrew Dillon
16:31 03 Dec 25
I have been a client of Optimize-U of Louisville for over a year, and the experience has been exceptional. Their comprehensive approach—including CBC panel monitoring, supplement guidance, and personalized diet recommendations—has consistently supported my health and fitness goals.I primarily work with Dylan Martin, RN, whose dedication and investment in my well-being have been outstanding. His expertise and genuine concern make the process both effective and enjoyable.If you are committed to improving your health and prefer a proactive approach over spending time in a doctor’s office addressing preventable issues, I highly recommend Optimize-U of Louisville. Their team will help you achieve—and potentially exceed—your wellness goals.
Kristen Estes
21:20 07 Nov 25
All of the staff and doctors are so friendly and helpful. They go out out of their way to make you feel truly cared for and heard. I can’t recommend it enough. It’s been completely life-changing!
Almira Quan
15:38 06 Nov 25
Jessica is amazingBeautiful friendly and very knowledgeableGreat experience
Nancy Martis
07:37 16 Oct 25
Very knowledgeable and caring. I'm so excited to get my life and health back. It's never to late to start.
Kevin Willis
17:10 29 Sep 25
Staff was great.Easy experience.Doctor was amazing
Christy Hall
20:06 24 Sep 25
I had my first appointment with Rachel today. She was so understanding & knowledgeable, im excited to work with her and Oprimize U to get my health back on track! The ladies at the front are super sweet & helpful too. Overall great experience and I highly recommend reaching out to see what they have to offer!
Jeremy Maudlin
18:45 30 Jul 25
Pleasant friendly and informative
Justin
19:22 25 Jul 25
Andy Conrado
22:33 17 Jun 25
♥️💪🔥🙏
Samantha Hufford
18:29 11 Jun 25
I had a great consultation with Jessica! Super knowledgeable and informative. I am super hopeful that our treatment plan will get me to feeling great again!
Will Jackson
17:05 29 May 25
Jeremy McManaway
12:17 21 May 25
Michael Shaheen
13:52 16 May 25
David Bufford
23:25 14 May 25
Heiko Myers
20:48 14 May 25
2 years and I haven't felt this good 25 years. Polite professional friendly helpful and knowledgeable. I could barely get out of bed in the morning and my son dragged me here and changed my life. Seriously I never knew a place like this existed and I am eternally grateful. God bless you all. I can never thank you enough.
Jen Mills
18:56 02 Apr 25
Santi Ramirez
18:14 28 Mar 25
Great customer care. Knowledgeable and professional staff.
Xavier Hunter
13:38 15 Mar 25
Really great folks in this establishment. Professional and knowledgeable always thankful for their readiness and accessibility. Keeping Kentucky healthy!
Clay Caple
13:26 15 Mar 25
Very quick and easy.Also very informative
Joe Scott
13:24 15 Mar 25
JEWELL and DYLAN will take care of you!!! Optimize you is the only place to go!!!
Holly Thrasher
14:49 24 Jan 25
Great place. Excellent customer service. Caring and compassionate!
Terra Renae
15:09 22 Jan 25
I couldn’t speak higher of OptimizeU! Everyone is so kind, professional and unbelievably knowledgeable! I appreciate that they truly take the time to listen to my concerns and create a completely customized treatment plan for me! I’m loving the results!!!
Brad Christiana
15:40 15 Jan 25
Jessica Matise and her staff provided excellent care. She was always available to answer my questions, my health and wellbeing was her primary concern.
Bryan Fiscus
18:04 14 Jan 25
lisa Nalley
17:10 02 Jan 25
I absolutely love OptimizeU Louisville. They have helped me turn my health around and I feel so much better. It’s only been a year now and I wish I had started this journey earlier. Thank you Rachel and Dylan and all the other amazing staff! Keep up the great work! Love you all! ❤️
William Johnston
17:34 16 Dec 24
I love their sauna and cold plunge. It's definitely an extremely intense process, but it helps tremendously with pain relief.
Rhonda Abbott
20:47 10 Dec 24
Extremely kind & helpful staff. Very pleasant experience, I won't be going anywhere else!
Valerie Arnold
16:29 09 Dec 24
Such a great experience! Dr. Jessica Matts has helped me understand and educate me about my POCS. When I first went to Optimize U it was just to check my horomones for body building purposes but I got so much more.For 4 years I thought something was seriously wrong with my menstrual cycle between the extremely short and heavy periods to mood swings so bad I thought I was possessed!! I seen several doctors who told me everything was fine.. it’s just my horomones.. “I was a lucky one to only have a 2 day period”..Fast forward to 4 YEARS LATER.. the wonderful Dr. Matt’s gave me so much insight and help me understand I have POCS! This has been life changing for me!
Steven Best
19:32 03 Dec 24
Great friendly service representatives and fantastic customer care.
kristan harmon
17:37 21 Nov 24
My husband and I both started here for various different services and love it. The facility and staff are all top notch!
Lisa Livers
20:51 14 Nov 24
I have been going to Optimize U for over a year now. I can't say enough great things about them. Rachel is who I deal with the most and she is absolutely the best. She always answers all my questions and always has my best interest in mind. I feel so lucky to have found Optimize U. I have lost about 25-30 pounds, and they have put me on hormone therapy which has made all the difference. If you are having any issues I highly recommend. From weight loss to hormones, I am so thankful. I can't imagine going anywhere else. They are all so friendly and so helpful. Call today you will not be sorry!!
KERI LOCK
11:29 14 Nov 24
I have had a very positive experience with Optimize U. Rachel and Dylan have helped me navigate my struggles through perimenopause. Rachel is always responsive and thorough with her feedback. I have already referred 2 of my friends who were not having a good experience with their providers. I highly recommend Optimize U. So glad I found them!
James Lock
11:24 14 Nov 24
Amazing staff and service! Rachel and Dylan are incredibly professional, knowledgeable, and responsive. Whenever I have a question, I can get an immediate response. The hormone therapy has been a game changer for me. I HIGHLY recommend Optimize U!
thomas sauer
04:24 11 Nov 24
Best place to go to hands down. No sales gimmick, they give you the best advice for you and not just what is good for business. I have had questions outside of my office visits and they are quick to respond. I don’t know why you would go anywhere else.
Michael Johnson
18:29 31 Oct 24
Absolutely amazing facility, can’t recommend enough.
Billy Wilson
06:00 18 Oct 24
G M
21:08 14 Oct 24
Tara Myers
21:50 02 Oct 24
Going to Optimize U has helped my mind and body be the best it can be. They will help you to feel your true you than anywhere else. Call them, you wont regret it
Chelsie Brown
19:12 09 Sep 24
Shelby Nichols
19:11 09 Sep 24
You guys are the best!
Tyler Woods
17:14 01 Aug 24
I was taken care of and given an extensive conversation and wealth of knowledge given my hormonal/weight loss needs. Haven't recieved medicine yet, but the practitioner and her nurses are wonderful to speak with. Say hi to Biggie if ya stop by!
Christopher Beverley
20:33 31 Jul 24
Yuri
13:03 22 Jul 24
Tyler
22:17 12 Jul 24
Great experience! 10/5 😜 Seriously, great experience though! Everyone was super nice, clean, wait time was not long at all. Dr. Jessica explained everything very well while going over results and straight to the point. Looking forward to treatment. Oh…parking was a breeze also. In and out in 25-30 minutes.
Christine Lund
16:24 02 Jul 24
Highly recommend this place to get your hormones checked. I worked with Rachel and she made me feel so good telling me hormonal numbers.
Thor’s Groot
15:33 25 Jun 24
Optimize U has been nothing but amazing. The results from the treatments have truly met all of my desired wish and wants. The staff from the front end receptionist to the medical staff have been TOP NOTCH! Every time I've called for any question big or small i am immediately greeted with a friendly voice that takes time to listen to my question. All medical appointments have been on point and very helpful. The medical staff take the time to listen while speaking with them without any distractions. If i could recommend this place i would 1,000 times again.
countryboy1291
15:28 18 Jun 24
I am in the beginning stages of my TRT treatment. Optimize U has been extremely friendly throughout the process. They answered all my questions and explained all the information in a very understanding way. I would highly recommend anyone who wants to know if TRT is right for them, go to Optimize U
John Miller
03:12 04 Jun 24
Great service and feeling great after a year!
Cortney Etherton
20:55 09 May 24
Dylan, Rachel and the staff are amazing. Very friendly, knowledgeable and keep up on the most recent technology and treatments. Highly recommend!
Meghan Mcpeek
15:18 03 May 24
Friendly professional atmosphere. I’m looking forward to using Optimize for my health needs!
Savannah Evans
19:43 24 Apr 24
Carmen Jamison
18:47 08 Apr 24
Jessica is amazing and easy to talk to. She helped me decide best treatment for me and answered all my questions. Her staff is also amazing. I would highly recommend them.
Danielle McHatton
19:11 05 Apr 24
Austin B
18:01 05 Apr 24
mitch fuzy
18:29 04 Apr 24
Fantastic staff, excellent facilities, and awesome results.
Haley Jackson
17:34 04 Apr 24
Best pricing for blood work. The staff is very friendly and extremely knowledgeable especially for all my pre and post prep needs! Highly recommend.
Yvonne Gemmer
14:53 01 Apr 24
Amy Davis
17:33 05 Mar 24
I have always had a great experience when I visit Optimize U. The staff is top notch! If you’re thinking about going - go! I have never felt better.
Megan ward
13:53 05 Mar 24
Great staff all the way around. Coming to a clinic with all sorts of emotions and leaving feeling more confident and hopeful is more than I could ever have hoped for. Thankful for this clinic!
Randall007 S
17:25 01 Mar 24
Dylan Martin
20:39 27 Feb 24
I’m a returning customer very happy to work with this team. Dr. Jessica is knowledgeable and made me feel like she would take the time to really listen to me. Very different than most of my Dr office visits over experienced over the years.
Lane Whelan
17:02 27 Feb 24
Brad Blankenship
17:55 09 Feb 24
Great products and service
Daniel Goldberg
22:04 08 Feb 24
I've been with Optimize U for two and a half years. I have nothing but good things to say about my treatment and results!
Angela Z
23:38 06 Feb 24
Aree T
18:28 06 Feb 24
Today, I went into Optimize U for skin concerns. Rachel and I talked about my concerns and what I wanted to achieve. Going over some options and what she suggested we came to an agreement what the game plans is. I can’t wait to get started! Thanks Rachel and staff at Optimize U for your professionalism and listening to my concerns. Love you all, & Biggie!
Julian Johns
17:59 06 Feb 24
They took my blood and I was in/out in about 10 minutes. I got my labs back in a convenient amount of time and my consultation was one day after that which was awesome! Everyone was great and easy to work with from top to bottom.
Terra Schrembs
20:38 22 Jan 24
I LOVE this place!!! Everyone is so friendly and passionate about what they do. I really appreciate that the providers take the time to genuinely listen to my concerns, and I never feel rushed. They offer a fine array of services and customized treatment options! So happy to have found OptimizeU!
outdoors & more
20:47 19 Jan 24
Rachel was very professional and polite. She answered all my questions and was very knowledgeable.
Tanya S
23:25 09 Jan 24
The office staff is friendly and I just really like Jessica. She has really helped me with my hot flashes and night sweats. She makes sure that the medication is working and that it’s the correct dose. Everyone should go see her and find out for yourself
Adam Clark
20:28 05 Jan 24
Ryan Hawkins
20:30 21 Dec 23
Autumn Cleveland
22:04 19 Dec 23
I have been coming here for my own health for years, and I have loved they handle each treatment and protocol…so much that I recommend all of myClients and friends to them, because I trust them. They explain everything throughly, are not pressuring, and they are genuine and caring people.
David Lara
13:15 11 Dec 23
Very good and professional team.
Kathy Wesley
16:40 06 Dec 23
I always love my trips to OptimizeU. The ENTIRE staff is so friendly and knowledgeable. I always feel so good about myself when I leave there. I could sit and chat with them all day.
Yilian Velazquez
17:51 05 Dec 23
Jessie Conlin
19:47 15 Nov 23
I'm super happy with my experience at Optimize U. Everyone there is friendly, attentive, and knowledgeable. Rachel explained everything clearly and answered all my questions. She also provided me with a customized plan that suited my needs and goals. I'm so excited to see the progress I'll be making. Highly recommend!!!
Tara Myers
19:55 13 Nov 23
You won’t go wrong coming here!! They’re better at helping you become your best self than anywhere I’ve ever dealt with. The staff is top notch!
Meg Palmer
19:13 13 Nov 23
Aimee McCaa
00:29 07 Nov 23
Jessica Matis APRN is just wonderful. She listens, reviews labs in details and ask appropriate questions regarding my on going health. I am glad my hormonal care is in her hands. 🙌🏻
Andrew Bowen
20:01 06 Nov 23
So freaking awesome. Wonderful experience and care. They really know what they’re talking about there when it comes to hormones.
lisa byerly
19:49 20 Oct 23
Chadd T
21:15 16 Oct 23
Brian Sparling
22:24 14 Oct 23
Very professional wonderful informed staff… very pleased
Daniel Dunn
18:15 10 Oct 23
Very knowledgeable and straight forward with any and all aspects of TRT and its benefits!!!
shelby eisenback
15:30 02 Oct 23
My experience with Optimize U has been nothing short of amazing! The medical staff are extremely professional, and informative, and thoroughly explained everything I needed to know about semaglutide, and why it could assist me with reaching my weight loss goals. I have to give a special shoutout to Rachel, as she has been WONDERFUL to work with, and is extremely responsive to all of my questions I have had throughout this process. I also love that they offer the in-body scan to keep track of my weight loss progression, including fat loss and muscle gain. My husband heard me rave about my experience, and saw the success I am having with semaglutide, and decided to become a customer, too! I will continue to recommend Optimize U to all of my family and friends, and cannot wait to start to use their other amazing services.
Kim Joseph
17:09 28 Sep 23
Rachel is the best!!...They offer so many wonderful services. The staff is so welcoming as well.
Jackie Scotts
18:34 26 Sep 23
Ashley Branham
00:56 24 Sep 23
I have been so impressed with this clinic and their knowledge about how to optimize my weight loss journey. Rachel is awesome and so relatable! She’s a hype girl for sure ! They seem to a wonderful staff who really cares about the health of their patients!
Maja Guandique
19:39 14 Sep 23
Customer care is unmatched! Dylan is amazing at taking care of patients, is super knowledgeable, and always goes the extra mile!
Aaron Kaplan
18:08 09 Sep 23
Terra Renee Arla
19:52 16 Aug 23
I am so impressed with Rachel's knowledge and professionalism. She thoroughly discussed my treatment and ensured my comfort throughout the duration of my visit. I am about 1 month into my Sculpt series, and I am already seeing drastic results on my once stubborn abdominal area. I also want to mention that the entire staff is so friendly and always makes me feel right at home. OptimizeU is truly a one stop shop filled with knowledgable professionals eager to help you reach your goals!
Rachel Ray
16:49 20 Jul 23
Love this business and my experience with them! The staff is so helpful to direct you to all options to achieve your goals. Dr Jessica is very knowledgeable about hormones and can help you better understand your lab panel. I’m so thankful I found them!
Marshall Mummert
20:13 06 Jul 23
Great place, great service. Friendly knowledge staff.
John Miller
21:22 21 Jun 23
So thankful I found Optimize U! The service is far better than any place I have ever been and they are very well educated on any question you may have. Friendly staff and a great environment. Love the fact that I have stepped outside my comfort zone and given Cryotherapy a try. Totally worth it! It’s TWO THUMBS UP from me!
Ashley Yoerg
18:02 21 Jun 23
I can not say enough good things about Optimizeu. The facility is immaculate, but also inviting. The staff is friendly, skilled and professional. The services I have received were performed accurately and efficiently in regards to time. I would highly recommend Optimizeu to any friend or family member.
Derek Gronda
23:03 20 Jun 23
After searching several places I came across optimize and haven’t looked back. Friendly professional and very knowledgeable staff. At 42 I’m thriving and crushing at life again, in all aspects. I’ve recommended several people by word of mouth including those closest to me, now I’m recommending you. If you’re reading this, chances are you’re not feeling yourself these days, not the best you can/could be, do yourself a favor and invest in yourself, your mental and physical health. Be the best you can be, thank me later!
Mary Meyer
20:54 06 Jun 23
I’ve been to Rachel several times for microneedling and Botox. She takes great care of me. She guides me to pick the treatments that will best meet my skin care goals. She takes a lot of time to make me feel comfortable. She’s very diligent about properly numbing me before the treatments that require it. She also keeps an open line of communication after treatments and can easily be reached if I have any follow-up questions or concerns. I cannot recommend her services enough. The treatment rooms are very clean, and the design is awesome. I tell everyone that I know that they need to go see her for any of their hormone or skin concerns.
Chelsie Skillman
03:41 31 May 23
I really have to have a lot of trust in the people taking care of me, and I definitely found that in Rachel at optimize U. I would send any of my family to her and know that they would be in great hands. I went to optimize U to get labs and an IV.The IV menu is super fun and I love all the options but Rachel was great & helped me choose based off of my overall goal for therapy. While my IV was going I got to sit in the most comfortable massage chair and watch TV, while Rachel checked on me multiple times. It was the most relaxed I’ve been in a while. Everything is very clean and it has the cutest decorations! I’m looking forward to monthly treatments to boost my health and wellness! I even had follow up for a semaglutide consult.Just all around good vibes, you can’t go wrong with anything here.
Juliana V
20:30 30 May 23
Optimize U is this magical place where you become the best version of yourself! My entire life, I had always struggled to lose weight and get in shape - I tried just about every exercise/ dieting program and then reached a point where I just accepted that this is the way I would always look. Jessica and Rachel, along with the entire Optimize U team, were able to meet me where I was at and help me gain control of my life. The Semaglutide injections helped me with my weight loss journey and allowed me to finally feel confident in my own skin for the first time ever - And I’m very excited to try Mounjaro next!Since having found out about Optimize U, and all of the services they provide, I have also become a huge fan of micro-needling and Dysport! After having these treatments, my face and skin look healthier and more vibrant than ever. Especially going into the summer months, it makes such a difference not feeling like you need to wear makeup to cover up all of those imperfections and wrinkles.I also have struggled with hair thinning which, as a woman, has made me feel very self conscious. Rachel introduced me to Nutrafol and it has made SUCH a difference! I have been taking Nutrafol along with Reds & Greens since December and my hair dresser has been amazed by all my new hair growth.Finally, I can’t say enough about the staff at Optimize U. They always make me feel so comfortable and validated in my expectations of what I am looking to achieve for myself. Jessica and Rachel are extremely knowledgeable about all of their products and services and I am so grateful for them!
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